John F. Boepple, a German immigrant, started the freshwater pearl button industry in Muscatine. Within 10 years, the population of Muscatine doubled, and the pearl button industry employed two-thirds of the labor force.
Button companies quickly spread throughout Iowa, as well as adjacent states and as far as Tennessee.
The facility included a pumphouse/boiler room (the lifeline of the station), a two and one-half story laboratory/dormitory, tank house, boathouse, temporary laboratory (offices), storehouse/carpenter shop, shell testing plant, blacksmith shop, barn, high- and low-pressure cisterns, and five cottages. The station also included a one-acre reservoir, 17 earthen ponds, and 14 small concrete ponds or holding tanks for experimental work. Mussel propagation research continued until 1931 when funding cuts forced the closing of mussel research. Efforts were transferred to a new station in Fort Worth, Texas.